This image is part of a series that was created for an open textbook, Cell Biology, Genetics and Biochemistry for PreClinical Students. The textbook will be available Late 2021.
Kindred Grey (2021). "Regulation of PFK1 by fructose 2,6-bisphosphate generated by PFK2."CC BY 4.0.
Glucose-6-phosphate bidirectional arrow with enzyme phosphoglucose isomerase to fructose-6-phosphate bidirectional arrow fructose-1,6-bisphosphate. Fructose-6-phosphate forward arrow with enzyme phosphofructokinase-1 and ATP arrow ADP to fructose-1,6-bisphosphate. F-2, 6-BP +. Fructose-1,6-bisphosphate backwards arrow with enzyme fructose-1,6-bisphosphate and loss of Pi to fructose-6-phosphate. Fructose-6-phosphate forward arrow with enzyme phosphofructokinase-2 fructose bisphosphatase-2 (bifunctional enzyme) and ATP arrow ADP to fructose-2,6-bisphosphate. Fructose-2,6-bisphosphate backwards arrow with loss of Pi to fructose-6-phosphate.